Dolasetron News
Inspired oxygen fraction of 0.8 compared with 0.4 does not further reduce postoperative nausea and vomiting in dolasetron-treated patients undergoing laparoscopic cholecystectomy.
Background. Postoperative nausea and vomiting (PONV) is one of the most frequent complications after general anaesthesia. Single-dose antiemetic prophylaxis has limited efficacy in high-risk patients. Adding a simple potential...
Drugs for preventing postoperative nausea and vomiting
Patients coming out of anesthesia after surgery may experience nausea or vomiting, and are frequently given drugs to prevent this. But the majority of patients won't benefit from these drugs, according to a large new review of...
Drugs given to stop nausea and vomiting after surgery help only a few people
Between 10 - 28% of people benefit from taking an anti-emetic drug to prevent nausea or vomiting after surgery - this means that if everyone was given the drug the majority of patients would be exposed to the risk of side-effects...
Drugs for Postoperative Nausea May Not Help Most Patients
Patients coming out of anesthesia after surgery may experience nausea or vomiting, and are frequently given drugs to prevent this. But the majority of patients won’t benefit from these drugs, according to a large new review of...
Lack of Effect of Aprepitant on Hydrodolasetron Pharmacokinetics in CYP2D6 Extensive and Poor Metabolizers
To prevent chemotherapy-induced nausea and vomiting, aprepitant is given with a corticosteroid and a 5-hydroxytryptamine type 3 antagonist, such as dolasetron.